Leadership
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Steven
M.
Fruchtman,
M.D.
President & CEO
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Dr. Fruchtman joined Onconova in January 2015 as Chief Medical Officer. He was promoted to President in July 2018 and to CEO in January 2019. He has extensive experience in large and small biopharmaceutical companies and has led successful clinical development programs while serving in senior positions at Ortho Biotech Products, Novartis, Allos Therapeutics, Spectrum Pharmaceuticals and Syndax Pharmaceuticals.
Previously, Dr. Fruchtman was on the faculty of the Mount Sinai School of Medicine and the Director of the Stem Cell Transplantation and Myeloproliferative Disorder Programs at Mount Sinai Hospital in New York City. He is an author of more than 170 lectures, presentations, books, chapters, and abstracts and serves as an external reviewer for multiple medical journals.
Dr. Fruchtman received his medical degree from New York Medical College with the distinction of membership in the Alpha Omega Alpha honorary medical fraternity.
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Mark
Guerin
Chief Operating Officer and CFO
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Mr. Guerin joined Onconova Therapeutics in September 2013 to augment the financial reporting, forecasting, and internal controls capabilities of the company following the IPO in July 2013. He was promoted to Chief Operating Officer and CFO in June 2022. Prior to joining Onconova, Mr. Guerin worked as an interim senior finance & accounting executive facilitating the post-acquisition integration activities of newly-acquired private equity portfolio companies. Previously, Mr. Guerin was the VP Finance & CFO of Cardiokine, Inc. through that company’s filing of a New Drug Application and the sale of the company. Prior to joining Cardiokine, Mr. Guerin was Director, Financial Reporting & Internal Controls at Barrier Therapeutics, Inc. during Barrier’s IPO and follow-on offering. Mr. Guerin started his career at Coopers & Lybrand in Philadelphia. He received his bachelor’s degree in Accounting from DeSales University and has earned the CPA, CMA, and CFM professional certifications.
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Victor
Moyo, M.D.
Chief Medical Officer
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Dr. Victor Moyo joined Onconova Therapeutics in June 2023 as Consulting Chief Medical Officer and transitioned to Chief Medical Officer in October 2023. Dr. Moyo is a highly experienced physician researcher and drug developer, with approximately 30 years of clinical research experience including 18 years in the pharmaceutical industry. He has held a variety of senior leadership positions with responsibility for a number of clinical development plans, IND filings, NDA filings, post-market development plans, notably including his work on such programs as Onivyde® for metastatic pancreatic cancer, epoetin alpha trial in myelodysplastic syndrome and the Doxil® trial in advanced ovarian cancer among others. He is also a named inventor on numerous granted patents and patent applications.
Most recently Dr. Moyo has been serving as Chief Medical Officer (CMO) of OncoPep, Inc. and Executive Vice-President, CMO and Head of R&D at L.E.A.F. Pharmaceuticals. Prior to that, he held various leadership roles as a Vice President Clinical Investigations or Medical Director at Merrimack Pharmaceuticals and the Centocor Ortho Biotech Services, LLC division of Johnson & Johnson.
Dr. Moyo earned his M.D. from the University of Zimbabwe. Following his move to the U.S., he went on to complete his internship and residency in Internal Medicine at the George Washington School of Medicine and Health Sciences and his fellowship in Hematology and Oncology at the Johns Hopkins University School of Medicine.
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Meena
Arora, MSc
Vice-President, Global Medical Affairs & Research and Development
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Meena Arora is a highly credentialed executive with experience in both pharmaceutical and emerging biotechnology companies, working in roles of increasing responsibility in medical affairs, regulatory strategy and scientific leadership in oncology, rare disease immunology, and inflammation. Over the course of her career, she has worked on development programs for notable products including Filsuvez®, Revlimid®, Imnovid®, Abraxane®, Vidaza® and CAR-T cell therapy (Breyanzi® and Abecma®).
Most recently, Ms. Arora served as Vice President/Head of Global Medical Affairs – Epidermolysis Bullosa (EB) for Amryt Pharma. Prior to that, she held various leadership roles as Medical Director or Associate Medical Director, as well as roles in Investigator Research and Medical Affairs at Celgene International. Ms. Arora has also held multiple advancing roles in medical and commercial development at GlaxoSmithKline and SmithKline Beecham.
Ms. Arora earned degrees in Pharmaceutical Science, Pharmaceutical Medicine and Biomedical Science with a Master of Science in Drug Development Science with studies in Biotechnology and Advanced Therapeutics from Kings College London and a Post Graduate Diploma in Pharmaceutical Medicine/Clinical Research from the University of Surrey. Ms. Arora received a Chartered Institute of Marketing Advanced Diploma from Cambridge Marketing College and earned a Post Graduate Diploma in Pharmaceutical Science and Bachelor of Science (Hons) in Biomedical Science from the Nottingham Trent University. Ms. Arora is the recipient of multiple industry awards and publication co-author.
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Matthew
Parris
Vice President, Clinical Operations
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Mr. Parris joined Onconova Therapeutics in August 2018 as Senior Director, Clinical Operations, and is responsible for overseeing and managing the Clinical Operations team and the cross functional project teams. He was promoted to Vice President, Clinical Operations in January 2021.
Mr. Parris has clinical development experience in multiple therapeutic areas, with a focus on Oncology and Hematology indications across a wide variety of therapeutic agents. He has over 24 years of industry experience, initially in Europe and since 2003 in the United States, holding management positions in contract research organizations as well as small pharma companies.
Previously, Mr. Parris served as Director of Clinical Operations for Inovio Pharmaceuticals, Vice President of Clinical Development for Eleison Pharmaceuticals, and Director of Clinical Operations at Aegerion Pharmaceuticals. He has a Bachelor of Science Degree, with honors, from Imperial College in London.
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Stephen
Cosenza, Ph.D.
Lead Scientist and Study Monitor
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Dr. Stephen Cosenza joined Onconova Therapeutics in January 2021 as Lead Scientist and Study Monitor. He is presently involved in the development of all compounds in Onconova’s pipeline, participates in business development activities, and assists with clinical operations. He has been a preclinical drug development consultant for Onconova since its inception in 1998. He has 36 years of experience in molecular biology, specializing in the regulation of the normal mammalian cell cycle and the initiation and progression of cancer cell growth. He has participated in preclinical and IND-enabling work for all of Onconova’s compounds that have been approved for clinical trials. Dr. Cosenza has extensive experience in cell culture and working with the in vitro and in vivo animal models required for the study and development of small molecular weight compounds as cancer therapeutics.
Previously, Dr. Cosenza worked at the Icahn School of Medicine at Mt. Sinai in the Department of Oncological Sciences and The Fels Institute for Cancer Research and Molecular Biology as Senior Researcher under the mentorship of Dr. E. Premkumar Reddy, one of Onconova’s founders. Dr. Cosenza has served as an external reviewer for various scientific journals and is an author of over 45 peer-reviewed articles.
Dr. Cosenza received his doctorate degree in the department of Microbiology and Immunology at Temple University School of Medicine. He performed his postdoctoral fellowship at the Wistar Institute and The Fels Institute for Cancer Research and Molecular Biology.